Skip to main content
. 2013 Dec 10;22(2):321–328. doi: 10.1038/mt.2013.259

Figure 2.

Figure 2

Fluorescence-molecular tomography scans showing, and bar graphs quantifying, nanoparticle (NP) delivery to tumor at various time points after treatment. (a) Top row: composite agent (MNCA) injection. Middle row: coinjection of microbubbles (MBs) and NPs. Bottom row: NP injection without microbubbles. Ultrasound (US)-treated tumors are denoted with white asterisks. Enhanced fluorescence intensity is evident with US application for the MNCA and MB+NP groups when compared to contralateral tumors that did not receive US. (b) Bar graph of fluorochrome concentration (% initial dose (ID) per gram of tissue) as a function of time. Bars are means ± SD. *Significantly different than MNCA at P < 0.05. +Significantly different than MB+NP+US at P < 0.05. #Significantly different than MB+NP at P < 0.05. All groups, n = 4.