Figure 5.
Effects of sitagliptin on AMPK- and AMPK-mediated Akt activation and MAPK phosphorylation in the aorta. Phosphorylative and total protein expression of AMPK (A), Akt (C), p38 (E) and ERK1/2 (G) in the aortic tissue of ApoE-/- mice. Quantitative analysis of pAMPK/AMPK (B), pAkt/Akt (D), pp38/p38 (F) and pERK1/2/ERK1/2 (H) in aortic tissue (n = 4 each). Values are mean ± SD; *p < 0.05, **p < 0.01.