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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Toxicol Pathol. 2013 Oct 31;42(1):140–147. doi: 10.1177/0192623313506794

Figure 2. Somatic mutation of PIK3CA/p110α in human cancers.

Figure 2

The p110α subunit consist of several different domains: ABD: adapter binding domain (AKA: p85 binding domain); RBD: Ras-binding domain; C2: C2 domain; helical: helical domain; kinase: kinase domain.