Table I.
Patient clinicopathological characterisitics.
| Characteristics | No. | % |
|---|---|---|
| Age (years) | ||
| <75 | 92 | 76.7 |
| ≥75 | 28 | 23.3 |
| Gender | ||
| Male | 65 | 54.2 |
| Female | 55 | 45.8 |
| Tumor location | ||
| Right | 57 | 47.5 |
| Left | 63 | 52.5 |
| Depth of invasiona | ||
| pT1 | 1 | 0.8 |
| pT2 | 8 | 6.7 |
| pT3 | 81 | 67.5 |
| pT4a | 22 | 18.3 |
| pT4b | 8 | 6.7 |
| Bowel obstruction | ||
| Yes | 14 | 11.7 |
| No | 106 | 88.3 |
| Lymph node involvementa | ||
| pN0 | 51 | 42.5 |
| pN1 | 51 | 42.5 |
| pN2 | 18 | 15.0 |
| Differentiation | ||
| High | 58 | 48.3 |
| Moderate | 52 | 43.3 |
| Poor/Muc/Sig | 10 | 8.3 |
| Lymphovascular invasion | ||
| Negative | 38 | 31.7 |
| Mild | 53 | 44.2 |
| Severe | 29 | 24.2 |
| Vascular invasion | ||
| Negative | 48 | 40.0 |
| Mild | 35 | 29.2 |
| Severe | 37 | 30.8 |
| CEA | ||
| <3.5 | 69 | 57.5 |
| ≥3.5 | 46 | 38.3 |
| CA19-9 | ||
| <37 | 88 | 73.3 |
| ≥37 | 22 | 18.3 |
| Postoperative chemotherapy | ||
| Yes | 69 | 57.5 |
| No | 51 | 42.5 |
| Recurrence | ||
| Yes | 31 | 25.8 |
| No | 89 | 74.2 |
| AQP1 scoreb | ||
| 0 | 64 | 53.3 |
| 2 | 13 | 10.8 |
| 3 | 17 | 14.2 |
| 4 | 26 | 21.7 |
a
UICC classification system, 7th edition.
b
The AQP1 score is the sum of the intensity score (0–2) and the extent score (0–2) and was 0 in 64 patients (53.3%), 2 in 13 patients (10.8%), 3 in 17 patients (14.2%) and 4 in 26 patients (21.7%). The incidence of AQP1-positive expression in colon cancer (score ≥3) was 35.9% (43/120). Right, ascending and transverse colon; Left, descending and sigmoid colon; Muc, mucinous carcinoma; Sig, signet ring cell carcinoma; CEA, carcinoembryonic antigen; CA, carbohydrate antigen.