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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: FEBS J. 2013 Dec 24;281(3):957–969. doi: 10.1111/febs.12661

Figure 1. ROCK inhibition prevented hyperoxia-induce changes in f-actin distribution.

Figure 1

Fluorescence images of F-actin in MLE-12 cells stained with rhodamine phaloidin. Compared to normoxia (A), hyperoxia for 48h (B) caused a thickening of the cortical F-actin and an increase in cell area. Treatment with the Rho Kinase inhibitor (Y-27632, 40 μM, C and D) prevented the changes in f-actin in the hyperoxia-treated cells (D). Scale bars are 50μm (representative images from 3 different experiments).