Table 2. Relative risk of death for patients with severe sepsis randomly assigned to intensive or conventional glucose control.
| Study name | N | Intensive glucose control (IGC) | Conventional glucose control (CGC) | Relative risk of death (IGC vs.CGC) | 95% CI for RR |
|---|---|---|---|---|---|
| Annane (COIITSS) | 509 | 117/255 | 109/254 | 1.07 | 0.88–1.30 |
| Arabi | 122 | 18/55 | 15/67 | 1.46 | 0.81–2.62 |
| Brunkhorsta | 535 | 98/247 | 102/288 | 1.12 | 0.90–1.39 |
| NICE-SUGAR | 1299 | 202/673 | 172/626 | 1.09 | 0.92–1.30 |
| Savioli | 90 | 14/45 | 13/45 | 1.08 | 0.57–2.03 |
| Van den Bergheb | 950 | 160/479 | 172/471 | 0.91 | 0.77–1.09 |
| Yu | 55 | 4/28 | 4/27 | 0.96 | 0.27–3.47 |
| ALL | 3560 | 613/1782 | 587/1778 | 1.04 | 0.95–1.14 |
a Brunkhorst (VISEP), IIT arm was stopped early so not all patients randomized to IIT vs. CIT. bVan den Berghe, patients classified post-hoc to severe sepsis or not.