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. 2014 Feb 6;9(2):e87981. doi: 10.1371/journal.pone.0087981

Figure 1. Cell-surface adhesion is actin-dependent.

Figure 1

A. Representative bright field (BF; left half of image) and IRM (right half of image) images of WT (AX3) cells on the 4 different surfaces. Scale bar = 35 µm. B. Quantification of average percent of cell in contact on each surface, for WT (AX3) cells and WT cells treated with 5 µM Latrunculin A. C. Representative BF and IRM images of WT (AX3) cells treated with Latrunculin A and plated on the 4 different surfaces. Scale bar = 35 µm. D. Quantification of average percent of cell in contact on BSA and PLL surfaces. WT cells were treated with different Latrunculin A concentrations, as indicated. For B and D, error bars indicate SEM of three independent experiments, each with over 30 individual cells analyzed. For B, *indicates statistical significance (p<0.05; ANOVA, Tukey test). For D, *indicates statistical significance compared to the control condition (*: p<0.05, T-test; **: p<0.005; T-test).