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Effects of pregnancy on HNF4α activity are target gene-specific. A and C, HNF4α recruitment to Hes6 (A) and Apoc2 (C) promoter was analyzed by ChIP assay (n = 4, mean ± S.D.; *, p < 0.05, one-way ANOVA versus virgin). B and D, mRNA expression of Hes6 (B) and Apoc2 (D) was determined by qRT-PCR (n = 4, mean ± S.D.; *, p < 0.05, one-way ANOVA versus virgin).
