Table 1.

Included studies

Study	Year	Number of patients	Criteria for initial diagnosis	Cement + antibiotics	Design	Mean followup (years)	Criteria for reinfection	MINORS score
Carlsson et al. [4]	1985	72	Not specified	Cement with gentamycin	Prospective	3.3	Pain, elevated CRP and ESR, loosening on radiographs or positive cultures	13
De Man et al. [6]	2011	72	At least 2 cultures or histology	Cementless or cement with gentamycin	Retrospective	2	Clinical or radiologic signs, CRP ≥ 10 mg/L, ESR ≥ 20 mm/hour	15
Garvin et al. [8]	1994	40	Deep aspiration and culture	Cement with gentamycin	Retrospective	5.7	Rerevision with positive cultures	11
Hope et al. [11]	1989	91	Deep tissue biopsy - CNS	Cement with gentamycin	Retrospective	3	Rerevision with positive cultures	11
Klouche et al. [13]	2012	84	Preoperative or intraoperative culture	Cementless or cement without antibiotics	Prospective	2	Positive culture from aspiration of joint	19
Morscher et al. [21]	1990	62	Clinical features/culture	Cementless or cement without antibiotics	Retrospective	3	Rerevision with positive cultures	16
Oussedik et al. [22]	2010	50	Clinical features/culture	Cementless or cement with gentamycin	Prospective	6.8	Rerevision with positive cultures	19
Sanzen et al. [24]	1988	102	Positive culture	Cement with gentamycin	Retrospective	6	Wound, pain with ESR ≥ 35 mm/hour and no other mechanical explanation	14
Wilson & Dorr [28]	1989	22	Clinical only	Cementless or cement without antibiotics	Retrospective	3.1	Sinus, fever, pain with ESR ≥ 35 mm/hour, radiographic changes. If doubtful aspiration performed.	17

MINORS = Methodological Index for NOn-Randomized Studies, maximum MINORS score is 24; CRP = C-reactive protein (normal, < 10 mg/L); ESR = erythrocyte sedimentation rate (normal, < 30 mm/hour); CNS = coagulase-negative staphylococcus.