Table 1.
Results of the meta-analysis
| Outcomes | Number of studies [references] | Number of patients | MD or OR (95% CI) | Heterogeneity | GRADE evidence | |
|---|---|---|---|---|---|---|
| Obese | Nonobese | |||||
| Surgical site infection | 24 [2, 5, 6, 8–10, 13–15, 17, 19, 20, 23, 24, 27, 28, 30–35, 39, 40] | 3493 | 89,690 | 2.33 (1.94, 2.79) | I2 = 49%, p = 0.007 | Moderate |
| Venous thromboembolism | 6 [2, 13, 15, 25, 27, 35] | 1643 | 83,442 | 3.15 (1.92, 5.17) | I2 = 0%, p = 0.63 | Moderate |
| Mortality | 6 [2, 9, 13, 15, 31, 32] | 2172 | 84,604 | 2.6 (1.50, 4.49) | I2 = 0%, p = 0.90 | Moderate |
| Revision | 9 [1, 2, 5, 21, 31–33, 39, 40] | 1039 | 1815 | 1.43 (1.05, 1.93) | I2 = 28%, p = 0.19 | Low |
| Operating time | 8 [10, 14, 31, 32, 34, 35, 39, 40] | 786 | 1658 | 14.55 (10.03, 19.07) | I2 = 44%, p = 0.09 | High |
| Blood loss | 7 [10, 14, 27, 31, 32, 35, 40] | 748 | 1548 | 28.89 (14.20, 43.58) | I2 = 38%, p = 0.14 | Moderate |
GRADE Working Group grades of evidence: High quality = further research is very unlikely to change our confidence in the estimate of effect; Moderate quality = further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate; Low quality = further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate; Very low quality = very uncertain about estimate.