Table 1.
Clinical pictures of patients with skeletal mesenchymal chondrosarcoma
| Case number | Age (years) | Sex | Tumor site at presentation | Treatment for the primary lesion | Metastasis, recurrence (months) | Site of metastasis | Treatment for metastasis or recurrence | Outcome (months) |
|---|---|---|---|---|---|---|---|---|
| Presented without metastasis | ||||||||
| 1 | 44 | M | Scapula | Cx (DI) + Ex | Mets (20) | Bone (multiple), lung | Cx (E) | DOD (51) |
| 2 | 29 | M | Scapula | Cx (VDI)* + Ex* + Rx* | Mets (6) | Lung | Cx (I)* + Ex (lung)* | DOD (26) |
| 3 | 45 | F | Rib | Ex* | None | None | CDF (91) | |
| 4 | 28 | M | Rib | Ex* + Cx* + Rx* | Mets (11) | Bone (spine) | Ex (T9, L1) + Rx | DOD (19) |
| 5 | 65 | F | Rib | Ex* + Rx* | Mets (49) | Bone (femur) | Ex (femoral head)* | DOD (139) |
| 6 | 23 | M | Rib | Ex* | Mets (15) | Bone (multiple) | Cx (MDIDa)* | DOD (41) |
| 7 | 25 | M | Dens | Ex* | Rec (38) | NA | DOD (52) | |
| 8 | 30 | M | Thoracic spine | Ex* + Cx (DI)* + Rx* | Mets (46) | Lung | Cx (DI) + Ex (lung) | AWD (99) |
| 9 | 31 | F | Lumbar spine | Cx (VDI) + Ex | Rec (21), Mets (41) | Bone (skull, spine) | Rx | AWD (41) |
| 10 | 25 | F | Lumbar spine | Ex* | Rec (11), Mets (11) | Bone (multiple) | Rx* | AWD (13) |
| 11 | 21 | M | Sacrum | Ex* + Rx* | Mets (99) | Lung, pancreas | Cx (DI)* + Ex (lung)* | DOD (128) |
| 12 | 38 | F | Sacrum | Ex* + Cx (BCytD)* | Mets (133), Rec (137) | Bone (spine) | Cx (I)* + Ex (L2)* | DOD (207) |
| 13 | 21 | M | Sacrum | Cx (VDI) + Ex | Mets (17) | Subcutaneous tissue | Cx (IrT)* + Rx* | DOD (34) |
| 14 | 27 | M | Femur | Ex* + Cx (CisD)* | Rec (84), Mets (153) | Bone (spine, pelvis) | Rx* + Ex (femur)* + Cx (I)* | DOD (194) |
| 15 | 26 | F | Femur | Cx* + Ex* | Mets (103) | Lung | Cx (I) + Ex (lung) | DOD (187) |
| Presented with metastasis | ||||||||
| 16 | 41 | M | Scapula | Cx (CisTax)* + Rx* | Bone (multiple) | Cx (CisTax)* | DOD (49) | |
| 17 | 14 | F | Thoracic spine | Cx (CisDaMet)* + Ex* | Lung | Ex (lung)* + Cx (IrT) | DOD (57) | |
| 18 | 16 | M | Pelvis | Cx (DI) + Rx + Ex | Lung | Cx (DI) + Ex (lung) | NED (40) | |
| 19 | 22 | F | Femur | Cx (DI) + Ex | Bone (spine) | Cx (DI) + Ex (T1) + Rx | DOD (114) | |
* Treatment outside of MD Anderson; M = male; F = female; Cx = chemotherapy; Ex = excision; Rx = radiotherapy; NA = information not available; B = bleomycin; Cis = cisplatin; Cyt = cytoxan; D = doxorubicin; Da = dacarbazine; E = etoposide; I = ifosphamide; Ir = irinotecan; M = mesna; Met = methotrexate; T = temozoromide; Tax = taxotare; V = vincristine; AWD = alive with disease; CDF = continuously disease-free; DOD = dead of the disease; NED = no evidence of disease. Mesen