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RPA2 hyperphosphorylation is critical for cell survival in response to HU but not IR. Clonogenic survival in MCF7 cells expressing RPA2-WT or RPA2-A after HU treatment (A) or exposure to IR (B). The cells expressing RPA2-WT or RPA2-A were treated with HU or IR at the indicated doses. The plotted points are on the averages of three to four experiments with standard deviations.
