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. 2014 Feb 7;5:38. doi: 10.3389/fimmu.2014.00038

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Copyright © 2014 Sun, Kudahl, Simon, Cao, Reinherz and Brusic.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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B-cell epitope on the structure of neutralizing antibody F10 binding HA protein (PDB ID: 3FKU). (A) Complex of F10-HA [A/Vietnam/1203/04(H5N1)]. The structure is a HA trimer of three identical copies (one of them is colored as cyan and green; the other two are in gray). Each copy contains the HA1 (cyan) and HA2 (green) chain, also the heavy chain of F10 (red), the neutralized epitope is highlighted in pink; (B) Close-up view of neutralized epitope identified on the structure (highlighted as pink surface).