Table 4.
Copy number variations of mtDNA in early-stage laryngeal cancer — univariate associations with clinicopathological characteristics
| Characteristics |
Copy number <4.02 |
|
Copy number >5.42 |
|
|---|---|---|---|---|
| OR * (95% CI) | P | OR * (95% CI) | P | |
| Age |
1.00 (0.94-1.06) |
0.93 |
1.03 (0.98-1.09) |
0.29 |
| Tumor invasion1 |
1.25 (0.39-4.04) |
0.71 |
0.48 (0.15-1.52) |
0.21 |
| Smoking history2 |
0.25 (0.05-1.31) |
0.10 |
0.17 (0.04-0.85) |
0.03 |
| Survival status3 | 1.09 (0.34-3.54) | 0.88 | 0.54 (0.17-1.69) | 0.29 |
*OR: odds ratio with 95% confidence interval; 1Tumor invasion (T1; T2; T3; T4); 2Smoking history (at least 10 pack-years); 3Survival status (Alive vs. Dead); The cases with 4.02-5.42 mtDNA copies were used as reference.