Table 2.
Changes in hemodynamic parameters in all experimental groups. Results are expressed as mean ± SEM. AA represents asiatic acid. * p < 0.05 vs. control group, # p < 0.05 vs. MS group (n = 8/group).
| Parameters | Control | Control + AA 20 mg/kg |
MS | MS + AA 10 mg/kg |
MS + AA 20 mg/kg |
|---|---|---|---|---|---|
| SP (mmHg) | 117.83 ± 1.9 | 116.61 ± 1.6 | 149.14 ± 3.6 * | 132.91 ± 1.0 *,# | 128.21 ± 1.7 *,# |
| DP (mmHg) | 76.96 ± 1.7 | 77.07 ± 1.5 | 98.51 ± 2.4 * | 88.47 ± 1.5 *,# | 88.28 ± 1.3 *,# |
| MAP (mmHg) | 90.58 ± 1.7 | 90.25 ± 1.4 | 116.05 ± 2.7 * | 103.08 ± 1.1 *,# | 101.59 ± 1.3 *,# |
| HR (beat/min) | 345.89 ± 8.6 | 344.76 ± 5.7 | 417.32 ± 14.6 * | 359.34 ± 4.9 # | 356.14 ± 6.4 # |
| HBF (mL/min/100 g tissue) | 7.38 ± 0.35 | 7.49 ± 0.40 | 4.00 ± 0.18 * | 5.91 ± 0.28 *,# | 6.33 ± 0.29 # |
| HVR(mmHg/mL/min/100 g tissue) | 12.44 ± 0.53 | 12.31 ± 0.73 | 29.42 ± 1.77 * | 17.73 ± 0.84 *,# | 16.27 ± 0.74 *,# |