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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Dec 14;274(3):372–382. doi: 10.1016/j.taap.2013.11.023

Figure 5. DZ and DZO decrease fibronectin lysate levels in astrocytes: reversal by antioxidants.

Figure 5

Astrocytes were treated for 24 h with 10 μM DZ or DZO followed by wash-out. In some groups, astrocytes were pre-treated for 3 h with the antioxidants melatonin (200 μM) or PBN (100 μM) before wash-out and OP treatment. Concentration of the positive control H2O2 was 20 μM. (A) Representative Western blot demonstrating a decrease in FN levels compared to untreated control, and the effect of PBN. (B) Quantification of all Western blot data. Results represent the mean (± SEM) of at least three independent experiments in which astrocytes were treated in duplicate. **Significantly different from control, p<0.01.