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. Author manuscript; available in PMC: 2014 Dec 26.
Published in final edited form as: Oncogene. 2013 Aug 5;33(26):3422–3431. doi: 10.1038/onc.2013.308

Figure 3. Interaction between MUC1-C and HER2 is upregulated in trastuzumab-resistant breast cancer cells.

Figure 3

A. SKBR3 (left) and SKBR3R (right) cells (1 × 104/well) were left untreated or treated with 80 nM trastuzaumb for 72 h. Cell number (mean±SE of three determinations) was determined by trypan blue staining. B. Lysates from SKBR3 and SKBR3R cells were immunoblotted with the indicated antibodies. C. Anti-MUC1-C precipitates from SKBR3 and SKBR3R cells were immunoblotted with the indicated antibodies. D. BT474 (left) and BT474R (right) cells (1 × 104/well) were left untreated or treated with 80 nM trastuzumab for 72 h. Cell number (mean±SE of three determinations) was determined by trypan blue staining. E. Lysates from BT474 and BT474R cells were immunoblotted with the indicated antibodies. F. Anti-MUC1-C precipitates from BT474 and BT474R cells were immunoblotted with the indicated antibodies.