(A) BMP-2, (B) collagen I and (C) osteonectin mRNA content of osteoblasts detected by qPCR in 7 days. Bars: 1, 1% aniline pentamer (AP)/poly(lactic-co-glycolic acid) (PLGA) alone; 2, PLGA with stimuli; 3, 0.5% AP/PLGA with stimuli; 4, 1% AP/PLGA with stimuli; and 5, 5% AP/PLGA with stimuli. &P<0.05 when compared to 4; #P<0.05 when compared to 2 and 3; *P<0.05 when compared to 2, 3, 4 and 5. n=3.