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. 2013 Mar 7;1(3):359–364. doi: 10.3892/br.2013.74

Figure 2.

Figure 2

Effect of aging on renal monocyte chemoattractant protein-1 (MCP-1) and collagen type I α 2 (COL1A2) expression in Tsukuba hypertensive mice (THM) and wild-type mice (WTM) (n=5). MCP-1 expression: (A) THM: slope (95% CI) 0.142 (0.0925–0.191), r2=0.671, P<0.01 and (B) WTM: slope (95% CI) 0.0267 (0.0137–0.0397), r2= 0.510, P<0.01. COL1A2 expression: (C) THM: slope (95% CI) 0.0251 (0.0159–0.0343), r2= 0.647, P<0.01 and (D) WTM: slope (95% CI) −0.00463 (−0.00857 to −0.000695), r2=0.254, P<0.05. Solid line: regression line; dotted lines: 95% CI of the slopes of the regression line. Significant differences were observed in slopes of the expression of MCP-1 and COL1A2 mRNA between THM and WTM (P<0.01).