Table II.
Association of rs2074380 and rs2074381 of ALPK1 with MI, as determined by the Chi-square test.
| Gene | Polymorphisms | dbSNP | MI (n=41) | Controls (n=5,730) | P-value (genotype) | P-value (allele) |
|---|---|---|---|---|---|---|
| ALPK1 | G→A | rs2074380 | 0.0198 | 0.0051 | ||
| GG | 40 (97.6) | 4,842 (84.5) | ||||
| GA | 1 (2.4) | 850 (14.8) | ||||
| AA | 0 (0) | 38 (0.7) | ||||
| HW P-value | 0.9370 | 0.9167 | ||||
| ALPK1 | A→G | rs2074381 | 0.0275 | 0.0075 | ||
| AA | 40 (97.6) | 4,888 (85.3) | ||||
| AG | 1 (2.4) | 811 (14.2) | ||||
| GG | 0 (0) | 31 (0.5) | ||||
| HW P-value | 0.9370 | 0.6725 |
Parenthetical data represent percentage values. ALPK1, α-kinase 1 gene; MI, myocardial infarction; dbSNP, single-nucleotide polymorphism database; HW, Hardy-Weinberg.