Table II.
Association between the methylation rate of WWOX gene promoter CpG islands and the clinicopathological characteristics of epithelial ovarian cancer.
| Clinicopathological characteristics | Positive no. | Negative no. | Methylation rate (%) | χ2 value | P-value |
|---|---|---|---|---|---|
| Age (years) | |||||
| >50 | 13 | 15 | 46.43 | 0.196 | 0.658 |
| ≤50 | 8 | 12 | 40.00 | ||
| Clinical stages | |||||
| I–II | 7 | 17 | 29.17 | 4.148 | 0.042 |
| III–IV | 14 | 10 | 58.33 | ||
| Pathological grading | |||||
| G1 | 5 | 9 | 35.71 | ||
| G2 | 9 | 11 | 45.00 | 0.602 | |
| G3 | 7 | 7 | 50.00 | 0.740 | |
| Pathological type | |||||
| Serous | 12 | 17 | 41.38 | 0.167 | |
| Mucinous | 9 | 10 | 47.37 | 0.683 | |
| Lymph node metastasis | |||||
| Yes | 6 | 7 | 46.15 | 0.042 | |
| No | 15 | 20 | 42.86 | 0.838 | |
| Ascites | |||||
| Yes | 14 | 16 | 46.67 | 0.277 | |
| No | 7 | 11 | 38.89 | 0.599 |
WWOX, WW domain-containing oxidoreductase.