Fig. 2.

clustal w alignment of the catalytic domain of Mpl with other metalloproteases. The primary sequence of Mpl was aligned to other bacterial metalloproteases using a BLOSUM protein matrix. Alignment includes elastase (Staphylococcus epidermidis), aureolysin (Staphylococcus aureus), bacillolysin (Bacillus subtilis subsp. amylosacchariticus), thermolysin (Bacillus thermoproteolyticus) and vibriolysin (Vibrio cholerae). Numbers on the right indicate amino acid positions. An asterisk indicates position 226 in Mpl.