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Apoptosis in the basal crypt cells of the distal colon of mice 6 h post AOM injection (10 mg/kg). Mice were oral gavaged daily for two weeks prior with oil. (a) control; (b) 6-bromoisatin 0.025 mg/g; (c) 6-bromoisatin 0.05 mg/g; (d) 6-bromoisatin 0.1 mg/g. Apoptotic cells with chromatin condensation characteristics are shown by arrows.
