Figure 6.

AD0157 inhibits microvessel outgrowth in the mouse aortic ring assay. (A) Representative samples of the aortic ring without or with treatment. In the top panel, the whole ring is photographed, and in the bottom panel, only one side is detailed (bar = 500 µm). (B) The results were calculated as the area occupied by new microvessels expressed as a percentage by the outgrowth observed in the controls, which we considered as having 100% vessel formation. The results are the mean ± SD of four aortic rings from different mice, * p < 0.005 versus the control.