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Selected examples of classical inhibitors of P-gp by generation.
| First Generation | Second generation | Third Generation |
|---|---|---|
| Verapamil Cyclosporine A Vincristine Reserpine Quinidine Tamoxifen Trifluoperazine |
(R)-verapamil Valspodar (PSC-833) Dexniguldipine Elacridar (GF120918) Biricodar Dofequidar |
Tariquidar (XR9576) Zosuquidar (LY335979) Laniquidar (R101933) ONT-093 (OC-144-093) Mitotane (NSC-38721) Annamycin |
