Table 5.
Multivariate analysis of perioperative (preoperative, intraoperative, and select postoperative) variables associated with organ/space SSI.
Factor | Any organ/space SSI, no. (%) | Multivariate analysis |
|
---|---|---|---|
OR (95% CI) | P value | ||
Age at surgery, per 10-y increment | NA | 1.6 (1.2–2.3) | .006 |
Smoking status | .01 | ||
No smoking history (n = 914) | 24 (2.6) | Referent | |
Former smoker (n = 357) | 6 (1.7) | 0.7 (0.3–1.7) | |
Current smoker (n = 98) | 6 (6.1) | 3.5 (1.3–9.6) | |
Vascular disease | .04 | ||
No (n = 1351) | 34 (2.5) | Referent | |
Yes (n = 18) | 2 (11.1) | 5.1 (1.1–24.5) | |
Prior MRSA infection | .02 | ||
No (n = 1364) | 35 (2.6) | Referent | |
Yes (n = 5) | 1 (20.0) | 25.3 (1.8–355.3) | |
EBL (per each doubling), mL | NA | 1.6 (1.1–2.1) | .008 |
Any lymphadenectomy | .03 | ||
No (n = 458) | 3 (0.7) | Referent | |
Yes(n = 911) | 33 (3.6) | 4.1 (1.2–14.1) | |
Small- or large-bowel resection | <.001 | ||
No (n = 1339) | 30 (2.2) | Referent | |
Yes (n = 30) | 6 (20.0) | 6.3 (2.1–18.5) |
Abbreviations: EBL, estimated blood loss; MRSA, methicillin-resistant Staphylococcus aureus; NA, not applicable; OR, odds ratio; SSI, surgical site infection.