Table 4.
Adjusted* hazard ratio (95% confidence interval) for mortality, by albuminuria category
| Albumin:Creatinine Ratio (mg/g) | ||||
|---|---|---|---|---|
| <30 | 30–299 | 300–999 | ≥1,000 | |
| British Columbia | Reference | 1.49 (1.26, 1.77) | 2.42 (2.09, 2.81) | 3.01 (2.51, 3.62) |
| CRIB | Reference | 1.65 (0.83, 3.27) | 2.15 (1.05, 4.40) | 3.56 (1.80, 7.02) |
| Grampian-ACR | Reference | 1.14 (0.05, 27.74) | 14.91 (0.60, 369.78) | 43.91 (1.90, 1014.98) |
| MASTERPLAN | Reference | 1.12 (0.58, 2.14) | 0.53 (0.19, 1.46) | 1.10 (0.41, 2.90) |
| Steno | Reference | 2.39 (0.96, 5.93) | 1.95 (0.81, 4.69) | 2.32 (0.94, 5.76) |
|
| ||||
| Overall | Reference | 1.50 (1.28, 1.75) | 1.85 (1.08, 3.16) | 2.73 (1.74, 4.26) |
|
| ||||
| Protein:Creatinine Ratio (mg/g) | ||||
| <50 | 50–499 | 500–1,499 | ≥1,500 | |
|
| ||||
| AASK | Reference | 1.82 (1.35, 2.45) | 1.93 (1.30, 2.87) | 2.60 (1.54, 4.40) |
| Grampian-PCR | Reference | 0.53 (0.22, 1.27) | 0.99 (0.40, 2.45) | 0.73 (0.25, 2.14) |
| MDRD | Reference | 0.99 (0.52, 1.88) | 2.17 (1.06, 4.46) | 1.80 (0.85, 3.80) |
|
| ||||
| Overall | Reference | 1.08 (0.54, 2.18) | 1.81 (1.30, 2.53) | 1.72 (0.90, 3.29) |
|
| ||||
| Dipstick Category | ||||
| −/± | + | ++ | +++ | |
|
| ||||
| Kaiser Permanente Northwest | Reference | 1.46 (1.16, 1.82) | 1.58 (1.28, 1.95) | 1.98 (1.48, 2.64) |
|
| ||||
| OVERALL | Reference | 1.46 (1.24, 1.71) | 1.80 (1.38, 2.35) | 2.26 (1.68, 3.04) |
*
Adjusted for age, sex, race, prior cardiovascular disease, smoking status, diabetes mellitus, systolic blood pressure, and serum total cholesterol concentration.
AASK: African American Study of Kidney Disease and Hypertension; CRIB: Chronic Renal Impairment in Birmingham; MASTERPLAN: Multifactorial Approach and Superior Treatment Efficacy in Renal Patients with the Aid of a Nurse Practicioner; MDRD: Modification of Diet in Renal Disease; Steno: Steno Type 1 Diabetes Study