Table 2.
Multivariable Cox regression analysis for overall survival in patients with advanced ovarian cancer
| Variable | N | Events | HR | 95% CI |
|---|---|---|---|---|
| Research activity |
|
|
|
|
| Non-trial hospital |
133 |
81 |
1 |
Reference |
| Trial hospital |
219 |
103 |
0.58 |
[0.42; 0.79] |
| Age |
|
|
|
|
| Continuous (5 years) |
352 |
184 |
1.24 |
[1.14; 1.34] |
| Performance status |
|
|
|
|
| ECOG 0/1 |
267 |
118 |
1 |
Reference |
| ECOG > 1 |
85 |
66 |
2.02 |
[1.38; 2.96] |
| Ascites |
|
|
|
|
| ≤ 500 ml |
172 |
74 |
1 |
Reference |
| > 500 ml |
180 |
110 |
1.77 |
[1.23; 2.53] |
| Comorbidity |
|
|
|
|
| None |
257 |
116 |
1 |
Reference |
| Present |
95 |
68 |
1.46 |
[1.08; 1.97] |
| Histology |
|
|
|
|
| Other |
89 |
40 |
1 |
Reference |
| Serous |
263 |
144 |
1.29 |
[0.85; 1.94] |
| Grade |
|
|
|
|
| G 1/2 |
166 |
81 |
1 |
Reference |
| G 3/4 | 186 | 103 | 1.10 | [0.80; 1.50] |