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Mediation analysis: Total, direct and indirect effects with 95% confidence intervals
| Effect (of trial hospital vs. non-trial hospital) | HR | 95% CI |
|---|---|---|
| Total effect |
0.58 |
[0.41; 0.80] |
| Direct effect |
0.67 |
[0.47; 0.92] |
| Indirect effect (through surgery) |
0.93 |
[0.84; 1.02] |
| Indirect effect (through chemotherapy) |
0.93 |
[0.84; 1.01] |
| Indirect effect (through both surgery and chemotherapy) | 0.87 | [0.75; 0.98] |
