Table 3.

Correlation results for all four formulations. Descriptors were selected via exhaustive search with AIC evaluation.

Formulation	Descriptor	Coefficient value	Standard error (p-value^a)
Buffer^b	(Intercept)	−0.25	0.48^(0.65)
	% α-Helix	−0.37	0.01^***
	% β-Sheet	−0.17	0.01^**
	MW	−0.53	0.01^***
	# S–S	−0.88	0.02^***
	# Free SH	−13.68	0.11^***
	T_m	−0.50	0.01^***
	a3vSA	155.36	2.70^***
	THSA	−0.07	0.03^(0.13)
	E_min	−16.25	0.30^***
	E_avg	3.27	0.31^**
	(E/L)_min	−53.63	0.34^***
	Peaks	11.23	0.05^***
Urea	(Intercept)	164.10	13.07^***
	Apolar	4.66E – 03	1.57E – 04^***
	pI	−7.16	0.80^***
	# S–S	5.85	0.38^***
	T_m	−2.17	0.09^***
	TA	−0.32	0.08^*
	Na4vSS	5.13	0.47^***
	E_avg	12.53	1.64^**
	L_avg	6.37	0.59^***
	(E/L)_min	−338.10	17.14^***
	(E/L)_avg	260.90	20.63^***
Sucrose	(Intercept)	159.17	2.77^***
	% β-Sheet	0.69	0.03^***
	MW	−2.84	0.08^***
	pI	−0.84	0.25^*
	T_m	0.62	0.03^***
	a3vSA	686.56	17.31^***
	NnHS	−19.03	0.49^***
	THSA	1.69	0.09^***
	TA	−2.44	0.06^***
	Peaks	3.89	0.20^***
Glycine	(Intercept)	387.91	19.91^***
	% α-Helix	−0.65	0.11^***
	% β-Sheet	−0.53	0.17^*
	NnHS	−23.98	1.88^***
	AATr	−2326.82	162.79^***
	THSAr	2247.68	155.16^***
	Na4vSS	3.04	0.31^***
	AvgE	13.64	1.33^***
	Peaks	−3.73	0.60^***

Significance codes for the p-values are:

^***

for <0.001,

^**

for <0.01,

for <0.05.

Buffer used in the formulation was potassium phosphate buffer (20 mM, pH 7.4).