. 2014 Feb;23(1):10–19.

Table 2.

Whole-brain activation results: 3×2 analysis of variance for study group (BDd, UDd, and HC adolescents) by condition (Go, NoGo) covarying for age and post-hoc tests between study groups

						MNI			Post-hoc tests
Brain region	Side	BA	Cl	Alpha Sim	Alpha p	x	y	z	F	t	pairwise p	Block	Groups

Cortical
Supplemental motor area	L	6	228	29	0.047	−18	12	60
DLPFC	L	9	82	17	0.04	−6	48	33	5.71	2.4	0.026	NoGo	BD>HC
Medial Frontal	L	10	95	20	0.042	−21	48	15	5.025	2.25	0.036	NoGo	BD>HC
Right Insula	R		43	18	0.041	54	−33	27					-
ACC	L	32	41	21	0.043	−3	27	39	9.46	3.09	0.006^*	NoGo	BD>HC
ACC									6.66	2.59	0.017	Go	BD>HC
ACC	L	33	50	16	0.039	0	18	18					-
Inferior parietal	R	40	264	32	0.047	63	−30	42					-
Superior temporal	L	41	121	10	0.039	−39	−33	12	11.28	3.38	0.003^*	NoGo	BD>HC
Superior temporal									11.06	3.35	0.004^*	NoGo	UDd>HC
Occipital	L	19	417	12	0.045	−39	−66	12	7.002	2.66	0.015	NoGo	BD>HC
Occipital									6.34	2.53	0.021	NoGo	UDd>HC
Subcortical
Caudate	L		78	12	0.05	−9	3	12	7.58	2.77	0.012	Go	BD>HC
									13.39	3.69	0.001^*	NoGo	BD>HC
									12.41	3.55	0.002^*	Go	UDd>HC
									11.05	3.36	0.004^*	NoGo	UDd>HC

Pairwise comparisons using t-tests for significant brain regions identified with ANOVA analysis (group by condition interaction) and significance level was identified as p < 0.008 (0.05/6) with an asterisk symbol under pairwise p values (corrected for multiple comparisons).

BA: Brodmann’s Area, CL: Cluster Size; AlphaSim: minimum cluster size for significance after AlphaSim correction, MNI: Coordinates according to the Montreal Neurological Institute, BDd: Bipolar Disorder in depressed state, UDd: Unipolar Major Depressive Disorder in depressed state, R=Right, L=Left, DLPFC: Dorsolateral Prefrontal Cortex, ACC: Anterior Cingulate Cortex.