Table II.
Location | Subjects | Main outcome measure | Intervention |
---|---|---|---|
Tromsø 1, Norway | Subjects with reduced glucose tolerance | Development of type 2 diabetes | 20,000 IU vitamin D3 per week or placebo |
Tromsø 2, Norway | Subjects with serum 25(OH)D < 50 nmol/l | Blood pressure, lipids, depression | 40,000 IU vitamin D3 per week or placebo |
Tromsø 3, Norway | Subjects with serum 25(OH)D < 50 nmol/l | Glucose sensitivity | 40,000 IU vitamin D3 per week or placebo |
Vienna, Austria | Kidney transplant recipients with 25(OH)D < 50 nmol/l | Graft function | 6800 IU vitamin D3 per day or placebo |
Seattle, USA | Type 2 diabetes with 25(OH) D < 75 nmol/l and urine albumin excretion ≥ 30 mg/day | Urine albumin excretion | 2000 IU vitamin D3 per day or placebo |
Dundee 1, Scotland | Age > 70 y, isolated systolic hypertension and 25(OH)D < 75 nmol/l | Blood pressure | 100,000 units vitamin D3 or placebo, taken at 0, 3, 6, and 9 months |
Dundee 2, Scotland | Adults with a past history of myocardial infarction | Change in endothelial function | 100,000 units vitamin D3 or placebo, taken at 0, 2, and 4 months |
Dundee 3, Scotland | Adults with resistant hypertension and 25(OH)D level < 75 nmol/l | Blood pressure | 100,000 units vitamin D3 or placebo, taken at 0, 2, and 4 months |
Aarhus, Denmark | Subjects with serum 25(OH) D < 80 nmol/l | PTH and calcium metabolism | 2800 IU vitamin D3 per day or placebo |
Leuven, Belgium | Patients with moderate to very severe COPD | COPD exacerbations | 100,000 units vitamin D3 or placebo every 4 weeks during 1 y |
25(OH)D, 25-hydroxyvitamin D; PTH, parathyroid hormone; COPD, chronic obstructive pulmonary disease.