Table I.
Clinicopathological data of 209 lung cancer patients.
| NRF2 gene status; rs6721961
|
||||
|---|---|---|---|---|
| Variables | CC | CA | AA | P-value |
| Mean age, years ± SD | 66.9±8.3 | 65.6±9.5 | 65.7±10.2 | NS |
| Stage | ||||
| I | 67 | 41 | 4 | 0.0373 |
| II–IV | 47 | 38 | 12 | |
| Gender | ||||
| Male | 105 | 70 | 15 | 0.6505 |
| Female | 9 | 9 | 1 | |
| Smoking, BI | ||||
| ≥800 | 43 | 28 | 4 | 0.6073 |
| <800 | 71 | 51 | 12 | |
| Age, years | ||||
| ≥65 | 50 | 37 | 11 | 0.1786 |
| <65 | 64 | 42 | 5 | |
| Pathological subtypes | ||||
| SCC | 75 | 48 | 11 | 0.7186 |
| Non-SCC | 39 | 31 | 5 | |
| FEV1 | ||||
| Mean ± SD | 2201.8±586.9 | 2295.7±633.6 | 2311.9±768.0 | NS |
| % FEV1 | ||||
| Mean ± SD | 71.7±10.4 | 71.9±11.3 | 68.5±11.5 | NS |
NS, not significant; BI, brinkman index; SCC, squamous cell carcinoma; SD, standard deviation; FEV1, forced expiratory volume in one second, smoker.