Table III.
Clinicopathological data of 209 lung cancer patients.
| NRF2 gene status; rs6726395
|
||||
|---|---|---|---|---|
| Variables | AA | GA | GG | P-value |
| Mean age, years ± SD | 66.7±8.2 | 68.0±8.9 | 65.4±8.9 | NS |
| Stage | ||||
| I | 8 | 39 | 66 | 0.5624 |
| II–IV | 9 | 27 | 60 | |
| Gender | ||||
| Male | 16 | 60 | 114 | 0.8868 |
| Female | 1 | 6 | 12 | |
| Smoking, BI | ||||
| ≥800 | 3 | 26 | 46 | 0.2427 |
| <800 | 14 | 40 | 80 | |
| Age, years | ||||
| ≥65 | 8 | 23 | 63 | 0.1320 |
| <65 | 9 | 43 | 63 | |
| Pathological subtypes | ||||
| SCC | 12 | 42 | 80 | 0.8447 |
| Non-SCC | 5 | 24 | 46 | |
| FEV1 | ||||
| Mean ± SD | 2132.4±647.2 | 2214.2±615.5 | 2277.5±618.6 | NS |
| % FEV1 | ||||
| Mean ± SD | 66.7±11.7 | 71.2±11.4 | 72.3±10.3 | AA vs. GG 0.043 |
NS, not significant; BI, brinkman index; SCC, squamous cell carcinoma; SD, standard deviation; FEV1, forced expiratory volume in one second, smoker.