Table I.
First author | Year | Ethnicity | Methods | No. (cases/controls) | Fibrosis (Y/N) | Genotype (cases/controls) | P-value for HWE | Refs. | ||
---|---|---|---|---|---|---|---|---|---|---|
| ||||||||||
CC | GC | GG | ||||||||
Vidigal et al | 2002 | Caucasian | Sequencing | 80/37 | Y | 1/0 | 11/3 | 68/34 | 1.000 | (14) |
Suzuki et al | 2003 | Asian | PCR-RFLP | 206/101 | Y | 0/0 | 0/0 | 206/101 | NA | (21) |
Zein et al | 2004 | African | Sequencing | 24/45 | N | 0/0 | 3/4 | 21/41 | 1.000 | (20) |
Wang et al | 2005 | Caucasian | LightCycler | 210/50 | Y | 0/0 | 32/8 | 178/42 | 1.000 | (19) |
Pereira et al | 2008 | Mixeda | PCR-SSP | 128/94 | N | 1/1 | 14/29 | 113/64 | 0.452 | (16) |
Armendariz-Borunda et al | 2008 | Caucasian | ARMS-PCR | 13/30 | Y | 0/6 | 0/13 | 13/11 | 0.706 | (18) |
Fang et al | 2008 | Asian | ARMS-PCR | 85/106 | N | 3/3 | 9/15 | 73/88 | 0.060 | (17) |
Romani et al | 2011 | Caucasian | PCR-RFLP | 164/169 | N | 1/2 | 18/16 | 145/151 | 0.101 | (15) |
Caucasian and African.
Y, yes, cases with fibrosis; N, no, cases without fibrosis; HWE, Hardy-Weinberg equilibrium; PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; NA, not available; SSP, sequence-specific primers; ARMS, amplification-refractory mutation system.