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. 2014 Jan 24;2(2):239–244. doi: 10.3892/br.2014.230

Table I.

Characteristics of studies included in the meta-analysis.

First author Year Ethnicity Methods No. (cases/controls) Fibrosis (Y/N) Genotype (cases/controls) P-value for HWE Refs.

CC GC GG
Vidigal et al 2002 Caucasian Sequencing 80/37 Y 1/0 11/3 68/34 1.000 (14)
Suzuki et al 2003 Asian PCR-RFLP 206/101 Y 0/0 0/0 206/101 NA (21)
Zein et al 2004 African Sequencing 24/45 N 0/0 3/4 21/41 1.000 (20)
Wang et al 2005 Caucasian LightCycler 210/50 Y 0/0 32/8 178/42 1.000 (19)
Pereira et al 2008 Mixeda PCR-SSP 128/94 N 1/1 14/29 113/64 0.452 (16)
Armendariz-Borunda et al 2008 Caucasian ARMS-PCR 13/30 Y 0/6 0/13 13/11 0.706 (18)
Fang et al 2008 Asian ARMS-PCR 85/106 N 3/3 9/15 73/88 0.060 (17)
Romani et al 2011 Caucasian PCR-RFLP 164/169 N 1/2 18/16 145/151 0.101 (15)
a

Caucasian and African.

Y, yes, cases with fibrosis; N, no, cases without fibrosis; HWE, Hardy-Weinberg equilibrium; PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; NA, not available; SSP, sequence-specific primers; ARMS, amplification-refractory mutation system.