Table IV.

Subgroup analyses based on ethnicity, genotyping methods, sample size and fibrosis under three genetic models with heterogeneity.

				Heterogeneity
Genetic model	Subgroup	OR (95% CI)	PZ	PQ	I2 (%)
C vs. G	Caucasian	0.87 (0.35–2.19)	0.77	0.03	65.4
	Sequencing	1.82 (0.69–4.84)	0.23	0.71	0.0
	ARMS-PCR	0.19 (0.00–8.84)	0.40	0.01	85.7
	Smalla	0.66 (0.26–1.67)	0.38	0.01	71.9
	Largeb	1.00 (0.61–1.65)	1.00	0.87	0.0
	Fibrosisc	0.60 (0.10–3.50)	0.57	0.01	78.0
	Non-fibrosisd	0.74 (0.39–1.38)	0.34	0.05	61.1
GC vs. GG	Caucasian	0.93 (0.39–2.18)	0.86	0.08	55.4
	Sequencing	1.68 (0.61–4.66)	0.32	0.83	0.0
	ARMS-PCR	0.20 (0.01–4.85)	0.32	0.04	77.6
	Smalla	0.58 (0.22–1.53)	0.27	0.02	67.6
	Largeb	1.07 (0.62–1.85)	0.80	0.70	0.0
	Fibrosisc	0.65 (0.14–3.10)	0.54	0.04	69.9
	Non-fibrosisd	0.70 (0.32–1.54)	0.89	0.02	68.2
CC+GC vs. GG	Caucasian	0.86 (0.33–2.23)	0.76	0.04	64.2
	Sequencing	1.78 (0.65–4.89)	0.26	0.77	0.0
	ARMS-PCR	0.17 (0.00–7.15)	0.35	0.01	84.0
	Smalla	0.59 (0.22–1.62)	0.31	0.01	72.2
	Largeb	1.04 (0.61–1.77)	0.90	0.78	0.0
	Fibrosisc	0.57 (0.10–3.35)	0.62	0.01	76.5
	Non-fibrosisd	0.71 (0.34–1.48)	0.92	0.03	67.0

^aSmall sample of subgroup analysis based on sample size (n≤250).

^bLarge sample of subgroup analysis based on sample size (n>250).

^cCases with chronic hepatitis C virus infection with fibrosis.

^dCases with chronic hepatitis C virus infection without fibrosis.

OR, odds ratio; 95% CI, 95% confidence interval; P_Z, P-value of Z test; P_Q, P-value of Cochran’s Q statistic; I², value of I² statistic; ARMS-PCR, amplification-refractory mutation system-polymerase chain reaction.