Table I.

Serum changes in pro-inflammatory cytokine levels.

A, Changes in IL-1 levels
IL-1 (IU/ml)	Sham control group	Pancreatitis group	Metastab group	CTX group	MTX group
2 h	0.60±0.085	1.02±0.119a	0.76±0.095	0.85±0.176b	0.82±0.153
6 h	0.60±0.085	1.13±0.17a	0.71±0.102b	0.75±0.13b	0.76±0.086b
24 h	0.56±0.055	1.15±0.129a	0.95±0.126b	0.91±0.171b	0.85±0.214b
B, Changes in IL-6 levels
IL-6 (IU/ml)	Sham control group	Pancreatitis group	Metastab group	CTX group	MTX group
2 h	74.33±16.26	98.83±12.43a	71.0±8.39b	72.83±8.01	85.0±10.7b
6 h	74.33±16.26	101.0±15.07a	70.0±7.21b	71.5±3.39b	74.83±21.68b
24 h	69.0±6.40	127.17±13.91a	98.83±11.11b	105.0±17.39b	97.67±18.88b
C, Changes in TNF-α levels
TNF-α (IU/ml)	Sham control group	Pancreatitis group	Metastab group	CTX group	MTX group
2 h	28.33±1.53	43.67±5.72a	38.0±7.54	38.33±2.81	39.17±7.11
6 h	28.33±1.53	48.67±5.32a	36.33±4.97b	35.0±7.40b	35.17±9.07b
24 h	23.5±1.87	55.33±12.79a	34.5±6.12b	37.5±12.01b	31.33±11.29b

^aStatistically significant difference vs. the sham control group (P<0.05).

^bStatistically significant difference vs. the pancreatitis group (P<0.05).

Metastab, methylprednisolone; IL, interleukin; TNF, tumor necrosis factor; CTX, cyclophosphamide; MTX, methotrexate.