Histopathological characteristics of the malignant melanoma. (A) Loose arrangement of melanoma cells with melanin deposits (hematoxylin and eosin staining, magnification, ×10). (B) Positivity for S-100 protein (immunostaining, magnification, ×20). (C) Positivity for anti-melanoma antibody (immunostaining, magnification, ×10). (D) Positivity for melanocyte/melanoma tumor antigen (immunostaining, magnification, ×10).