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Representative results of E-cadherin immunostaining. (A) E-cadherin was commonly found to be expressed on the membranous surface of the cancer cells of papillary thyroid microcarcinoma. (B) Approximately 20% of the cases were negative for E-cadherin expression. (C) E-cadherin expression was diminished at the invasive front in one-fourth of the E-cadherin-positive tumors. (D) E-cadherin was frequently expressed in the metastatic lesions in the lymph nodes.
