Table I.
Variables | No. of patients |
---|---|
Age, years [median (range)] | 56 (26–78) |
Histological type | |
Serous | 101 |
Endometrioid | 18 |
Clear cell | 26 |
Mucinous | 11 |
First-line regimen | |
TC | 135 |
DC | 10 |
CPT-P | 6 |
CAP | 5 |
No. of first-line chemotherapy cycles [median (range)] | 6 (1–13) |
Debulking surgery | |
Complete | 31 |
Optimal | 39 |
Suboptimal | 86 |
Response to first-line chemotherapy | |
Complete response | 107 |
Partial response | 26 |
Stable disease | 4 |
Progressive disease | 19 |
CR according to histological type [CR/non-CR (%)] | |
Serous | 73/101 (72.3) |
Endometrioid | 12/18 (66.7) |
Clear cell | 16/26 (61.5) |
Mucinous | 6/11 (54.5) |
Recurrence sites after CR | |
Intraabdominal | 45 |
Intrapelvic | 44 |
Distant | 18 |
Second-line regimen | |
Platinum-based | 70 |
Non-platinum-based | 37 |
TC, paclitaxel/carboplatin; DC, docetaxel/carboplatin; CPT-P, irinotecan (CPT-11)/cisplatin; CAP, cyclophosphamide/adriamycin/cisplatin; CR, complete response.