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. 2014 Feb 7;9(2):e87822. doi: 10.1371/journal.pone.0087822

Figure 8. rflaA:Ova-induced IL-6 and IL-10 secretion from mDC are mediated by different signaling pathways.

Figure 8

C57BL/6 mDC derived from C57BL/6 wt, MyD88−/−, Trif−/−, or MyD88−/−Trif−/− mice were co-cultured with OT-II CD4+ T cells and stimulated with equimolar amounts of rOva, rflaA, rflaA+rOva, or rflaA:Ova, respectively. Levels of IL-6, IL-10, and IFN-y in the culture supernatants were analyzed after 72 h. Results are means ± SD of two independent experiments. Please note that results from C57BL/6 and Myd88−/− cells were already published in Schülke et al., 2011 JACI.