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. 2014 Feb 6;14:15. doi: 10.1186/1471-2466-14-15

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Copyright © 2014 Hsu et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Design of the procedure. In all patients, the target sedation level before bronchoscopy was an Alaris auditory-evoked potential index (AAI) level between 25 and 40 and a Ramsay sedation scale (RSS) of 5 or 6. During bronchoscopy, patients were randomized to the auditory-evoked potentials (AEP) group or the RSS group. The sedative was adjusted in accordance with the AAI level or the RSS level. The AAI, heart rate, and mean arterial pressure were recorded every 5 min before flexible bronchoscopy and after flexible bronchoscopy.