Figure 9. Effects of adipocyte-specific knockout of PKC-λ on and basal and insulin-stimulated (treatment for 10 min with 1 mU/g body weight injected intraperitoneally) phosphorylation states of hepatic aPKC, Akt1/2 and FoxO1 in ad lib fed mice. Mice in these studies were 5–7 mo old. Values are mean ± SEM of 6 determinations, and representative blots are shown above bargrams. Asterisks indicate P values: *P < 0.05; **P < 0.01; ***P < 0.001. Abbreviations: WT, wild type mice; AλKO, knockout mice.