Table 1.
Case | Age (years) sex | Eye | PCNSL prior to PIOL | Result of vitreous biopsy
|
Imaging characteristics
|
VA after vitrectomy | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytological diagnosis | IL-10 (pg/mL) | IL-6 (pg/mL) | Ratio of IL-10/IL-6 | Retinal finding | FA | FAF | OCT | |||||
1 | 57 male | Right | Yes | Class V | 5,000 | 415 | 12.0 | Diffuse subretinal infiltration | Leopard spot like pattern | N/A | Hyperreflective infiltration at the level of RPE, separation of Bruch membrane from the RPE, destruction of RPE and IS/OS, hyperreflective signals in inner retina | HM |
2 | 57 male | Left | No | Class V | 3,150 | 102 | 30.9 | Small lesion mimicking drusen | Hyper, inverting fluorescence pattern of FAF | Granular pattern | Nodular hyperreflective infiltration at the level of RPE and above RPE, separation of Bruch membrane from the RPE, destruction of RPE and IS/OS, hyperreflective signals in inner retina | 1.0 |
3 | 67 male | Left | Yes | Class III | 1,820 | 66.5 | 27.4 | Large whitish yellow spot | Hyper, inverting fluorescence pattern of FAF | Hypofluorescence and hyperfluorescence surrounding mass lesion | Hyperreflective infiltration at the level of RPE, separation of Bruch membrane from the RPE, destruction of IS/OS, hyperreflective lesions in the form of bands above RPE, hyperreflective signals in inner retina | 0.15 |
Abbreviations: FA, fluorescein angiography; FAF, fundus autofluorescence; HM, hand motion; Hyper, hyperfluorescence; Hypo, hypofluorescence; IS/OS, inner segment/outer segment junction; IL, interleukin; N/A, not available; OCT, optical coherence tomography; PCNSL, primary central nervous system lymphoma; PIOL, primary intraocular lymphoma; VA, visual acuity.