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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Oncogene. 2013 May 20;33(18):2307–2316. doi: 10.1038/onc.2013.187

Figure 4. Calcium regulates the induction of some genes implicated in hypoxia-mediated EMT.

Figure 4

Assessment of mRNA levels of A) vimentin, B) N-cadherin, C) CD44/CD24, D) Snail and E) Twist with normoxia or hypoxia (1% O2) in MDA-MB-468 breast cancer cells with intracellular calcium chelation (BAPTA-AM). Bar graphs show mean ± S.D. for nine individual wells from three independent experiments. The effect of BAPTA-AM on gene expression was assessed using two-way ANOVA with Bonferroni’s multiple comparisons post-tests. * P < 0.05.