2.

Targets of CaP-related miRNAs and their function

CaP-related miRNA	Function	Targets and function	Methods for validating targets	Ref.
miR-20a	oncomiRNA	E2F1–3: cell cycle regulator, pro-apoptosis	reporter assay, WB	[39]
miR-125b	oncomiRNA	Bak1: pro-apoptotic regulator	microarray, reporter assay, WB	[33]
miR-126*	ts-miRNA	SLC45A3: related to prostate malignancy	tansfection, PCR, WB	[40]
miR-146a	ts-miRNA	ROCK1: myosin phosphorylation; PI3K activation	tansfection, NB, WB	[32]
miR-221/222	oncomiRNA	p27Kip1: inhibition of cell cycle	tansfection, reporter assay, WB	[41]

oncomiRNA, oncogenic miRNA, ts-miRNA, tumour-suppressor miRNA; WB, Western blotting, NB, Northern blotting.