2.

Proteins which were upregulated in diabetic when compared to non-diabetic rat hearts both treated with resveratrol

Spot number	Protein	Function	Mowse score	Mw (theor., kDa)	pI (theor.)	Mw (on gel, est. kDa)	pI (on gel, est.)	Relative abundance	P-value
1536	Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial precursor	Fatty acid oxidation	935	36	8.1	27	6.3	1.4	3.00E-05
406	Stress-70 protein, mitochondrial precursor (75 kDa glucose-regulated protein) (GRP 75)	Proliferation, aging, chaperone	830	74	6.0	70	5.5	1.4	0.01418
502	Dihydrolipoyllysine-residue acetyltransferase comp. of pyruvate dehydr. complex, mitochondrial precursor	Citric acid cycle	914	68	8.8	60	5.5	1.5	0.000653
228	Glycogen phosphorylase, brain form	Glycogenolysis	1418	97	6.3	100	6.4	1.6	0.01427
440	Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8)	Chaperone	416	71	5.4	65	5.6	1.7	0.02859
1889	Adenine phosphoribosyltrans-ferase (APRT)	Nucleotide salvage pathway	371	20	6.2	19	5.6	1.8	0.003842
1034 1038 1045	Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial precursor	Citric acid cycle	686 785 758	44	8.5	45 45 45	6.6 6.1 6.4	1.9 1.6 1.6	0.001224 0.03529 0.0356
1747	Glutathione S-transferase Mu 2 (GSTM2–2) (Glutathione S-transferase Yb-2)	Oxidative stress/anti oxidant	464	26	6.9	22	6.7	2.0	0.005773
662	Catalase	Oxidative stress/anti oxidant	1330	60	7.1	55	7.1	2.1	0.00077
977	α-enolase (2-phospho-D-glyc-erate hydro-lyase) (Non-neural enolase) (NNE)	Glycolysis	736	47	6.2	45	8.0	2.6	0.000602
1212	Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain, cardiac muscle beta isoform)	Structural protein	1203	224	5.6	40	4.9	2.7	0.000241
1061 1082	Elongation factor Tu, mitochondrial precursor	Protein synthesis	769 661	50	7.2	45 45	6.3 6.2	1.5 3.5	0.001967 4.42E-05
1584	Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1)	Oxidoreductase	742	31	8.2	26	6.8	3.6	0.004523
1819	Apolipoprotein A-I precursor (Apo-AI)	Fat metabolism	550	30	5.5	21	5.5	7.4	4.49E-05