1.
General characteristics of sham, MI, MI+SAR and MI+CIL animals 8 weeks after surgery.
| SHAM (n = 19) | Ml (n = 15) | MI+SAR (n = 18) | MI+CIL (n = 12) | |
|---|---|---|---|---|
| Body weight (g) | 599 ± 14 | 521 ± 9 * | 527 ± 11 * | 523 ± 10 * |
| Ventricular weight (g) | 1.37 ± 0.04 | 1.58 ± 0.04 * | 1.41 ± 0.04 # | 1.43 ± 0.04 # |
| Ventricular weight/Body weight ratio (mg:g) | 2.38 ± 0.03 | 2.99 ± 0.08 * | 2.55 ± 0.05 # | 2.57 ± 0.07 # |
| RV (g) | 0.31 ± 0.02 | 0.48 ± 0.04 * | 0.36 ± 0.04 # | 0.37 ± 0.04 # |
| Scar weight (g) | — | 0.16 ± 0.01 | 0.15 ± 0.01 | 0.16 ± 0 |
| Lungs wet/dry ratio | 4.53 ± 0.06 | 5.11 ± 0.10 * | 4.95 ± 0.08 # | 4.95 ± 0.11 # |
| Liver wet/dry ratio | 3.18 ± 0.02 | 3.31 ± 0.06 | 3.30 ± 0.05 | 3.27 ± 0.03 |
Values are means ± SEM. MI, myocardial infarction; SAR, sarpogrelate; CIL, cilostazol; LV, left ventricle; RV, right ventricle. *P<0.05, significantly different from sham. #P<0.05, significantly different from MI.