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. Author manuscript; available in PMC: 2014 Feb 8.
Published in final edited form as: Genes Brain Behav. 2011 Jul 7;10(7):720–733. doi: 10.1111/j.1601-183X.2011.00711.x

Figure 2. Acquisition of α7-nAChR mutant mice in the RAM.

Figure 2

α7-nAChR KO and WT littermate mice were trained to perform a win-shift search strategy using the RAM. Doors to the arms closed between arm choices for 1 second to limit simple turnleft/right strategies. KO mice took more sessions to acquire the win-shift rule compared to WT mice, as measured by the number of arm entries prior to repeat [WM span (a)]. The strategy used by these mice also changed with increasing sessions, indicative of a simple strategy being used less as time went on, as measured by strategyCV (b). Data are presented as mean ± SEM, *P < 0.05 when compared to WT mice on that session day.