Table 4.
Grade 3–4 acute and late stage toxicities
| Characteristic | Surgery-based group | RT-based group | P -value |
|---|---|---|---|
| Total no. patients |
148 |
290 |
|
| Grade 3–4 acute toxicity |
|
|
|
| Neutropenia |
50 (33.8%) |
91 (31.4%) |
0.610 |
| Anemia |
12 (8.11%) |
41 (14.1%) |
0.067 |
| Gastrointestinal reactions |
15 (10.1%) |
13 (4.48%) |
0.036 |
| Small bowel obstruction |
3 (2.03%) |
0 (0.00%) |
|
| Diarrhea |
12 (8.11%) |
13 (4.48%) |
|
| Grade 3–4 late stage toxicity |
|
|
|
| Chronic radiation intestinal injury |
11 (7.43%) |
12 (4.14%) |
0.144 |
| Small bowel obstruction |
2 (1.35%) |
0 (0.00%) |
|
| Proctosigmoiditis |
9 (6.08%) |
12 (4.14%) |
|
| Chronic radiation cystitis |
6 (4.05%) |
7 (2.41%) |
0.378 |
| Lower limb lymphedema | 10 (6.76%) | 6 (2.07%) | 0.017 |